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There are limitations to our analyses that may limit interpretation of the results for a broader population of smokers.
The PCP in IPAH patients is greater than normal but methodological limitations related to the occlusion technique may limit interpretation of these data in isolation.
The authors concluded that PCP in IPAH patients is greater than normal, but methodological limitations related to the occlusion technique may limit interpretation.
Although low power may limit interpretation of negative results, the prospective design minimizes bias.
However, heterogeneity among trials in adopting these measures and in reporting their results may limit interpretation of the pooled results.
As with any inhibitor, off-target effects may limit interpretation.
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Also, the fact that different variables had different time frames may further limit interpretations of the associations.
Whereas the mean PCP measured using the artery occlusion technique was greater than normal in our patients with IPAH, the methodological limitations related to this technique may limit the interpretation of these data in isolation.
In addition to the already mentioned limitations of this study, some further aspects which may limit the interpretation of present results must be discussed.
A limitation of TIMER is that it was an open-label study, which may limit the interpretation of the results.
Yet shortcomings in PRO trial design, methodology and reporting may limit the interpretation of PRO data and its potential to inform patient-centred care [13].
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CEO of Professional Science Editing for Scientists @ prosciediting.com