Sentence examples for may limit clinical from inspiring English sources
The observed beneficial effects on muscle growth may depend on signaling pathways other than myostatin that are not specific to muscle, and the modulation of non-muscle tissue physiology may limit clinical application.
Resulting donor site morbidity such as impairment of smell or anosmia may limit clinical use.
However, some measurement instruments require extended training of the assessor (e.g., ACMC), which may limit clinical applicability [ 19- 21].
The aim of this study was to identify an Ad serotype suitable for use as a vascular gene therapy vector: assessing efficacy in vitro and ex vivo and determining any seroprevalence in the population that may limit clinical use.
Further, low cord blood serum phosphate may limit clinical stability since it is required for glucose tolerance, tissue sensitivity to insulin [ 25], as well as glucose-induced insulin secretion [ 26].
Particularly, for SCP patients this may be difficult, as the need to place such children in a confining bore of an MRI device may limit clinical application, due to anxiety effects on muscle excitation.
The progressive increase in plasma sodium levels, in contrast with the sharp increases sometimes reached when other therapies are used, may help to limit clinical complications.
This experimental porcine study of 5-hour continuous lipopolysaccharide infusion has several limitations that may limit its clinical translation.
While it is possible that confounders of the measurement may limit its clinical utility, the tools are now available to make the clinical measurements.
The rapid clearance and elimination of HA intra-articular injection may limit its clinical usage; therefore, the improvements of longer residence time may extend the therapeutic benefit and clinical applications.
The dose limiting toxicity of decitabine was identified as myelosuppression and this toxicity plus the limited demethylation in tumours and eventual re-methylation of genes may limit the clinical use of decitabine when used alone in solid tumours.
