Exact(1)
Although events upstream of activation of caspase-3 were not investigated and may play a role, the expression of high levels of caspase-3 in active RA indicate that inhibition of apoptosis may largely occur downstream of caspase-3 activation.
Similar(59)
The sharp declines have largely occurred in the past two years.
For example, glycolytic pathway genes were activated by CORT, and increasing evidence suggests that glycolysis in the brain may occur largely within astrocytes (98, 99).
The presence of backcross hybrids in the wild in a number of these species indicates that introgression may occur, largely in pairs of less divergent species, but even in some rather divergent species.
The rapid recruitment of TIP47 upon oleic acid loading (Wolins et al. 2001; Ohsaki et al. 2006b) suggests that the LD growth in this condition may occur largely by non-fusion mechanisms.
It may largely be a lottery.
Whether in meteorites or on Earth, prebiotic chemistry may have occurred largely in an aqueous environment, as water is a ubiquitous component of the solar system and the Earth's surface.
Given that PARP-dZF2 cannot bind DSBs yet shows undiminished activation by SSBs in vitro, our results further suggest that in response to MNNG, PARP-1 mediated NAD degradation and mADPR accumulation may be occurring largely in response to SSBs, as MNNG induces primarily SSBs [42], [43].
Improvements in LN staging practice may have occurred largely due to educational presentations that created awareness, and self-initiated changes undertaken by pathologists.
Improvements in LN staging practice may have occurred largely due to educational presentations that created awareness about the new recommendations, and self-initiated changes undertaken by pathologists.
In conclusion, it has become apparent over the past 15 years that filovirus infections pose a definite public health risk in those areas where contacts with the still largely unknown reservoir may occur and early warning systems as well as preparedness plans are hard to implement.
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Justyna Jupowicz-Kozak
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