The biological function of the unusual product retention remains uncertain, but may involve a mechanism of directed delivery to the membrane-bound enzyme that follows CL in the ubiquinone pathway.
The mechanism(s) by which nasal continuous positive airway pressure (CPAP) is effective in the treatment of Cheyne-Stokes respiration (CSR) in patients with congestive heart failure (CHF) remains uncertain, and may involve an increase in total oxygen body stores (dampening), changes in central and peripheral controller gain, and/or improvement in cardiac function.
The reason for the loss of renal Dnase1 is uncertain, and may involve different processes.
The reason for the difference in efficacy between the two cured cells is uncertain but may involve the ability to support replication or the level of receptor expression.
However, in general these studies were unable to evaluate effects of heavy drinking, and the processes by which alcohol affects BMD remain uncertain but may involve effects of increased levels of estrogen and calcitonin (Maurel et al. 2012).
The mechanisms that result in arterial ageing are uncertain but may involve an increased production of reactive oxygen species, which decrease the bioavailability of nitric oxide (NO), which is a molecule produced by the vascular endothelium that plays an important role in the regulation of vascular tone and function (3).
The pathogenesis of these changes is uncertain but it may involve both a cytotoxic response and a delayed hypersensitivity (type IV) response to Co-Cr particles.
Although the pathogenesis of this phenotypic change remains uncertain, available data suggest that this may involve the acquisition of a combination of increased proliferative potential and resistance to apoptosis [ 3].
This may involve the setting-up of hatcheries in some cases so that populations are not dependent on uncertain natural factors for annual recruitment.
The recommended choices may involve tradeoffs.
