Sentence examples for may involve suppression from inspiring English sources
This indicated that normal NHERF1 function may involve suppression of cell cycle progression [ 25].
The mechanism by which zidovudine potentiates the cell death effects of gemcitabine may involve suppression of the Akt-GSK3 β pathway.
The antitumoral effect of Ttzm in breast cancer may involve suppression of Akt and extracellular signal-regulated kinase (ERK) signaling and of cell cycle regulators, including cyclin D1 and p27 [ 9].
In summary, we show that chronic exposure to FGF21, a naturally-occurring hormone and potent insulin sensitizer, markedly extends lifespan in mice through a mechanism that may involve suppression of the GH/IGF-1 signaling axis in liver.
This protective effect of PPUS against brain ischemic injury involves its ability to attenuate BBB disruption and brain edema, which may involve suppression of ischemic brain injury-induced downregulation of ZO-1 and occludin and overexpression of MMP-9.
The bone-protective effects of estrogen may involve suppression of inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-α), which in turn activate inducible nitric oxide synthase (iNOS).
A viable strategy for improving the therapeutic response to gemcitabine may therefore involve suppression of the NF-κB pathway.
These data indicate that the antiproliferative effects of raxofelast in H2O2-stimulated rat aortic smooth muscle cells may involve the suppression of intracellular reactive oxygen species formation and the inhibition of ERKs by inactivation through PKC and MEK1,2 and down-regulation of c-myc expression, regardless of Ras activation.
The underlying mechanism of this anti-inflammatory effect of S14 may involve the suppression of certain cytokines, e.g. TNF-α.
Such a cost may involve growth suppression such as that reported in A. thaliana plants with a cytosolic ascorbate peroxidise gene knocked out [33].
These results suggest that the mechanism of COE to inhibit EMT process may involve the suppression of TNF-α-induced NF-κB/Snail signal pathway.
