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Finally, quantification of fat elimination in faeces showed a modest albeit significant increase in fecal lipid output in HFD-fed Cnr2 −/− mice, as compared to WT counterparts (Table 1), by a mechanism that may involve inhibition of pancreatic lipase gene expression (Cadoudal et al, preliminary results).
The mechanism underlying this observation is unclear, but may involve inhibition of tumour angiogenesis.
These results suggest that mechanism by which CD109 decreases ECM and CCN2 production in SSc and normal skin fibroblasts may involve inhibition of Smad2/3 phosphorylation.
The mechanisms of the aprepitant effect may involve inhibition of nuclear factor (NF -κB activatioNF -κBubstactivationviewed [ 5, 6]).
Another potential mechanism impairing rac-pindolol tubular secretion may involve inhibition of the organic cation transport system, as has been demonstrated with co-administration of cimetidine [ 24].
This suggests that part of the anti-proliferative action of ATRA may involve inhibition of the PI3K pathway, which is often turned on in breast cancer cells.
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Recent work suggests that the anti-inflammatory function of Nrf2 may also involve inhibition of NF-κB [ 123, 125], although the underlying mechanism is elusive.
During the onset of EAE, the effects may also involve inhibition of prostaglandin synthesis, which in mice is a consequence of R- to S-flurbiprofen inversion and thus S-enantiomer-mediated cyclooxygenase inhibition.
The DNA damage-induced cell cycle arrest in the G1 and S phases may partly involve inhibition of the activity of G1 CDKs by the specific CDK inhibitor, p21 [ 42].
Therefore, the mechanism(s) for the inhibition of tumor formation and growth by NSAIDs may in part involve inhibition of stromal COX-2.
The decrease in Isc induced by ACh may involve the inhibition of Ba(2+ -inhibitable K+ currents, as the addition of 100 microM BaCl2+ -inhibitablel solution inhibited Isc and also completely inhibited the response produced by ACh.
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may involve surgery
may involve counseling
may be inhibition
may involve money
may escape inhibition
may augment inhibition
may involve payment
may involve dopamine
may initiate inhibition
may mediate inhibition
may suggest inhibition
may involve counselling
may reflect inhibition
may maximize inhibition
may bypass inhibition
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