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It may involve general mechanisms shared by other inflammasome activators, such as potassium efflux that is regulated by K+ channels like P2X7, or by the sensing of reactive oxygen species that are released during cell stress.
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Recruitment to primary care studies is especially complex, because it may involve organisations (general practices or primary care trusts), practitioners (general practitioners, nurses and other primary health care professionals) or patients, in various combinations.
Or it may involve a general armistice (i.e., a total cessation of all hostilities) such as the French armistice agreement of 1940.
Confirmation of a misplaced line warrants line removal, which may involve a general anaesthetic in paediatric patients.
The present structural results convey a simultaneous description of both binding partners of an LRP ligand complex and open a route to a broader understanding of the binding specificity of the LRP receptor, which may involve a general four-residue receptor ligand recognition motif common to all LRP ligands.
The mutation may involve a general cancer gene that triggers carcinogenic events independent of cell lineage.
The mechanism for these associations is unknown but may involve more general effects on the hypothalamic pituitary adrenal axis (Kapoor and Jones, 2005).
For instance, care for a person with diabetes mellitus type II may involve a general practitioner, a dietician, and a physiotherapist, but also an endocrinologist.
Nevertheless much breast cancer surgery is still delivered by general surgeons, so care for individual women may involve surgeons from general as well as plastic/reconstructive surgery backgrounds now working together in an 'oncoplastic multidisciplinary team'.
Arms races may involve a more general competitive acquisition of military capability.
We now consider how to extend this reasoning to the overall bottlenecking process, which in general may involve several phases of quiescent and cycling dynamics with different kinetic parameters.
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