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Although the mechanistic basis for this remains to be determined, it is possible that the important role of NAP1L3 in HSCs maintenance and haematopoietic restoration shown in this study, may involve epigenetic transcriptional regulatory mechanisms of the HOXA genes in a similar way to what has been previously reported14,26,29,34,36,37,42.
Also, we have offered other explanations for twin discordance that may involve epigenetic changes [34].
Altered expression of tropomyosins in hypoxic neuroblastoma cells may involve epigenetic alterations to HMW promoter regions.
It has recently been reported that such ROS production may involve epigenetic silencing of subtelomeric chromatin [ 25, 26].
The underlying regulatory mechanism may involve epigenetic mechanisms controlling mammary gland development that remain preserved during malignant transformation (Stingl and Caldas, 2007; Rijnkels et al, 2010).
Joubert et al. addressed the hypothesis that the diverse effects of maternal smoking during pregnancy may involve epigenetic modifications such as DNA methylation.
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The response may involve an epigenetic component and gender-dependence in mice.
The biological mechanisms responsible for the onset and exacerbation of asthma symptoms in children may involve the epigenetic regulation of inflammatory genes after environmental exposures.
Our results establish a potential mechanism connecting HPV positivity and expression of CDKN2A transcripts that is separate from tumor suppressor proteins p53 and pRb, and may involve direct epigenetic regulation of ARF transcription.
There is now considerable evidence that changes in gene expression which involve epigenetic alterations may be an important factor in prostate cancer progression, and development of panels of epigenetically modified genes as markers of disease progression is of considerable topical interest.
Some processes involve epigenetic mechanisms.
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may underlie epigenetic
may comprise epigenetic
may involve multiple
may demonstrate epigenetic
may control epigenetic
may involve extra
may involve different
may involve qualitative
may modify epigenetic
may inhibit epigenetic
may reprogram epigenetic
may involve blinking
may trigger epigenetic
may overturn epigenetic
may escape epigenetic
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