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They also suggest that the beneficial actions of cholesterol-lowering agents such as statins may involve effects on the rate of lipolysis in adipocytes.
The mechanism behind these SCr changes remains unknown, but may involve effects of tofacitinib on inflammation.
Future investigations of potential antiangiogenic mechanisms may involve effects of AW464 on these redox active molecules.
However, in general these studies were unable to evaluate effects of heavy drinking, and the processes by which alcohol affects BMD remain uncertain but may involve effects of increased levels of estrogen and calcitonin (Maurel et al. 2012).
The mechanisms by which DR reduced CT-2A tumour angiogenesis and growth are not yet clear, but may involve effects on both the tumour cells and the tumour-associated host cells.
If associations do indeed reflect intrauterine effects, potential mechanisms may involve effects of high prenatal carbohydrate, protein, and fat intakes on greater maternal glucose concentrations in pregnancy, which may program offspring appetite.
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However, the therapeutic benefit of HDAC inhibitors may well extend beyond simple chromatin remodelling and may also involve effects on the acetylation of essential transcription factors such as BCL-6.
On the other hand, the mechanism by which the AP-1 binding site in the NR2B gene mediates ethanol effects on transcription, as previously reported by others, may involve indirect effects of CpG demethylation.
It is therefore possible that the beneficial effects reported in patients receiving treatment with bisphosphonates may involve direct effects on tumour cells in bone as well as inhibition of osteoclast-mediated bone resorption.
The use of organic pigments from other classes may involve undesirable effects on the curing process of PU paint films [10].
"It is suggested that the misestimates are due to a complex of factors that may involve sociological effects, such as attitudes to social roles and perception of power relations".
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