The actual mechanism of recruitment differs greatly between different viral families, and may involve direct contacts between the IRES and ribosome without involvement of any initiation factors as in the case of the Dicistroviridae intergenic IRESs, or may be mediated by subsets of translation factors that are also involved in ribosome recruitment during normal cap-dependent translation.
Such reactions, when occurring in the presence of large concentrations of the reactants, may involve direct hole transfer.
Added modulation of cell apoptosis and proliferation may involve direct nanoparticle effects on intracellular signalling mechanisms [107].
Although the origin of this base promotion remains unclear, the depolymerisation mechanism may involve direct nitration of the phenolic.
We have tested the hypothesis that activation of BCR-ABL may involve direct interaction between BCR sequences and the tyrosine kinase regulatory domains of ABL.
Three of these types, i.e. when the attack occurs at the level of measurement, decoding and feedback, may involve direct manipulation of a person's neural computation.
Current methods for increasing penetration may involve direct introductions into the brain such as intraventricular or intracerebral injection, infusion, and implantation and may increase toxicity risks and non-uniform drug dispersals [11].
These findings suggest that although topoisomerase inhibitors interfere with DNA synthesis in the S phase, their induction of greater than G2 polyploid blocks may involve direct or indirect inhibition of chromosome condensation.
It may involve direct participation of the members of a society in deciding on the laws and policies of the society or it may involve the participation of those members in selecting representatives to make the decisions.
The mechanisms underlying acute renocardiac syndrome are not clearly understood, but may involve direct (e.g., cytokines, sympathetic tonus and renin angiotensin aldosterone system) or indirect (e.g., fluid and electrolyte imbalances) effects of acute kidney injury on the heart [27, 28].
