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As detailed below, however, the ability of cannabinoids to evoke pain under some circumstances may involve action at non-CB1/CB2 targets.
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In the present study we provide evidence that topical administration of 6, 8-dithiouric acid accelerates wound healing in mice by a mechanism that may involve actions of the UA analog on fibroblasts, keratinocytes and vascular endothelial cells.
Therefore, the ability of VU0467154 to reverse MK-801-induced hyperactivity may involve actions at corticostriatal terminals to normalize the function of overactive (disinhibited) excitatory projections from the cortex to the striatal complex.
Pain often originates from mechanical action, although, where tissue damage results, the stimulus may involve chemical action as well.
The mechanisms behind these changes are not understood but may involve the action of soluble β-amyloid (Aβ) on electrical networks.
This result points to a more complex role of Hfq in L. monocytogenes and suggests that Hfq exerts a stimulating effect on the protein level, activity and/or secretion of the chitinases by a mechanism that may involve the action of other Hfq-dependent sRNAs in L. monocytogenes.
Mitochondrial dysfunction in AD may involve the action of APP and Aβ, as they were reported to target the mitochondria and cause mitochondrial dysfunction (Caspersen et al., 2005; Devi et al., 2006; Manczak et al., 2006).
"Advancing our interests may involve new actions and policies to confront threats like terrorism, but the president and the Democratic Party believe these practices must always be in line with our Constitution, preserve our people's privacy and civil liberties, and withstand the checks and balances that have served us so well," the platform states.
However, because of the functional proximity of M1 corticospinal neurons to the spinal apparatus, to avoid overflow of their activity into unintended, overt movements during processes that involve action observation, it may be important to attenuate or block that activity.
Keeping sales momentum going may involve less dramatic action but it is no less important.
The Court's power to review a law or an official act of a government official is part of its supervisory jurisdiction, and at its fullest may involve quashing an action or decision and ordering that it be redone or remade.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com