Sentence examples for may involve aberrant from inspiring English sources

For example, nickel increased H3K9 dimethylation by inhibiting the demethylating enzyme JMJD1A [29], [29] suggesting that the carcinogenic effects of nickel may involve aberrant changes in gene expression through epigenetic mechanism(s).

Decreased DNA methylation may involve aberrant expression of structural and matrix proteins or reduced DNA integrity resulting in premature aging of venous tissue as essential step within the pathogenesis of primary varicose veins.

Another input relevant to cell trafficking alteration may involve the aberrant expression of an activation marker(s) (e.g., CD69) and a potential defect in lymphocyte egress from lymphoid organs [51], within a broader picture of multi-level biological impacts of the coronin-1A deletion.

In summary, spatially and evolutionarily conserved IDRs in kinases may influence their functions, which can be exploited for targeted therapies in diseases including those that involve aberrant cytoskeletal remodeling.

Results may also provide a foundation for future studies on SCA1, SCA2, SCA3, SCA15, SCA16, and other IP3R1-associated ataxias, which all involve aberrant calcium signaling.

This may involve neurotrophic factors withdrawal, aberrant neurotransmission, synaptic loss, excitotoxicity and prion-like spread of pathogenic misfolded proteins like trans-synaptic spread of Aβ [ 3].

One of the earliest stages of MSA pathogenesis may involve the overexpression or aberrant localisation of α-synuclein in oligodendrocytes, where it becomes fibrillar [ 69] and forms GCIs [ 39].

Genetic evidences that the TAL-1 aberrant overexpression may involve t(1 14) (p32 q11) translocation or submicroscopic interstitial 1p32 deletion with resulting fusion of TAL1 with SIL promoter were provided.

The aberrant systemic arterial supply may involve a single or multiple vessels, and the latter accounts for 15 20% of pulmonary sequestration cases [ 18].

Alternatively, TDP-43 may involve functions other than exon splicing and the importance of the aberrant splicing that was detected by us is separate.

The results indicated that the aberrant location of Cx43 protein could be responsible for the progression of hepatocarcinogenesis, and the mechanism may involve defects of Cx genes in post-translational processing.