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Most strategies have used fold-change threshold values, but variability at low signal intensities may invalidate this approach and it does not provide information about false-positives and false negatives.
NMA methods depend on the assumptions that effect measures are additive on the selected scale and that relative treatment effects are comparable; [ 8] heterogeneity between trials may invalidate this assumption.
While some literature results [ 17] shows that outbreaks of other respiratory pathogens like HMPV, dual out breaks, etc. may invalidate this assumption, the ICD9 signal observed in our data does not present any evidence of these issues, giving confidence that our assumption to use ICD9 codes as a proxy for RSV cases is valid for our study.
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This may invalidate the assumption (A1) above.
This confounding may invalidate the interpretation of our results.
Previous studies pointed out that this upper bound may invalidate the normality assumption of ordinary least square (OLS) method.
He can't do anything else as it may invalidate the rest of his work.
Pre-existing medical conditions can add to the premium, but they should always be declared or you may invalidate the terms of your cover.
Realistic production systems usually encounter various of unexpected disruptions, which may invalidate the original schedules, and thus rescheduling becomes essential.
In [21] we address possible objections such as the influence between distance and number of products bought, which may invalidate the effect of the Product Sophistication.
"Hinterland counties" within the still-regulated states, but farther away from the state borders, are used as a second control group to consider and reject the possibility that cross-border spillover of deregulation effects may invalidate the empirical design.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com