The lack of a homologous 3D model of this enzyme made it impossible to investigate the impact on its structure caused by these insertions, but they likely created additional loops in the nematode proteins that may introduce novel functional features specific to Nematoda.
The effect of anesthetics may introduce certain variability to the cardiac functional parameters.
The use of clinically available human cells in functional tissue engineering may introduce additional factors that may influence the utility of preconditioning as we have described here.
Use of RT for benign disease such as PVNS may introduce concerns about the risks of functional impairment and radiation-induced malignancy.
We are aware of the circularity that simulations may introduce, however we have assumed that functional sites coevolve in their physico-chemical properties and that this coevolution is diluted by the stochastic noise generated throughout the evolution of proteins.
This scenario suggests a functional role for isomiRs that may introduce a new layer of complexity in gene expression regulation.
Although mechanisms are still to explore, the positive correlation of SNP rs6886 as a possible functional relevant CapG variant with FTC may introduce a novel interesting link between ovarian and fallopian tube carcinomas.
Keeping the functional analysis as the last step, however, may introduce a bias in itself due to both false negative genes in the selection step and wrong clustering.
This may introduce some bias towards the larger agreement observed with the STRING predicted functional associations dataset.
By not including an overt task in the current functional MRI study, we aim to avoid the potential confounds this may introduce.
