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The traditional methods of adjusting for "potential confounders" may introduce conditional associations and bias rather than minimize it.
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Let's introduce conditional probability by definition: Definition.
Third, as diabetes and fasting glucose values are plausibly intermediate variables between TCF7L2 and retinal phenotypes, our analyses conditional on diabetes/fasting glucose values need to be interpreted with caution as this method may introduce confounding [ 25].
But that may introduce its own problems".
This may introduce confounding effects.
Metals may introduce plasmonic effects.
This may introduce two problems.
When you start introducing conditional statements into the equation, it very quickly complicates things.
To construct genetic gain-of-function models of Sirt1 in mice, we introduced conditional Sirt1 alleles into the Rosa26 locus.
For example, branch optimization can introduce new conditional branches.
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