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Hence, stress responses that are related may interact positively, while distantly related responses may interact negatively.
While there is a possibility that treatments may interact negatively, or in other complex ways, we consider this a reasonable prediction.
Thus, having the BDNF p.Val66Met polymorphism may interact negatively with the experience of childhood trauma, which may in turn affect the development of the hippocampus and the DLPFC [ 45].
In case the patients were using benzodiazepines regularly or occasionally during the daytime to control their anxiety, we advised them to taper and stop usage or to switch to an antidepressant before starting the CBT program, since these drugs may interact negatively with exposure treatment [ 18].
In this case, even though the same alleles may be favored in both populations due to the similarity of their environments, they may not exhibit the same mutations or fix them in the same order, such that when the populations come back into contact, incompatible alleles may interact negatively in hybrids creating pre- and/or postzygotic reproductive barriers.
While mild, antibiotics have been known to diminish the effectiveness of birth control pills and may interact negatively with other drugs.
Similar(54)
ABA and JA may also interact negatively under saline conditions.
In the inset of Figure 5C, we have also marked IgC5 positively charged residues, which potentially may interact with negatively charged lipids.
Although these polymers bind efficiently to nucleic acid, their highly positive charge may interact with negatively charged serum proteins and tissue components in vivo, therefore hindering the effective transfection.
We tempt to speculate that this mutant is partially folded/misfolded for two possible reasons: When close to the cytoplasmic surface, the positively charged side chains may interact with negatively charged phosphate groups at the lipid bilayer surface or may promote packing of TMs by H-bond formation with neighboring residues, resulting in proper folding and/or insertion of the protein (39, 40).
Another possibility is that environmental factors acting at resolutions finer than the data considered herein may be interacting negatively with the biology of the species.
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