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As the two antimetabolites may interact at several biochemical levels along their pathways of activation, we investigated whether gemcitabine (GEM) affects 5-FU pharmacokinetics in cancer patients.
These profiles might indicate genes that may interact at different times and different tissues during infection (Kawahara et al. 2012).
In a crude way, figure 3 serves to show how adatoms may interact at higher coverage levels.
In addition, antagonists may interact at unique binding sites not normally involved in the biological regulation of the receptor's activity to exert their effects.
Antagonists mediate their effects by binding to the active (orthosteric = right place) site or to allosteric (= other place) sites on receptors, or they may interact at unique binding sites not normally involved in the biological regulation of the receptor's activity.
Estrogen and BPs may interact at the level of BM cancer cell dormancy.
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Several CNS drugs may interact directly at the receptor level or indirectly affecting one or more neurotransmission system.
Therefore, it appears that BiP protein may interact with at least two viral components (RdRp and capsid) in NNV-infected cells, and that the interaction between BiP and viral proteins is crucial to the outcome of NNV infection.
Thus, HIV may interact with DCs at various mucosal sites during sexual transmission and at intestinal mucosa during parturition.
These results indicate that the PRE may interact with AP2, at the very least, but AP2 is neither the sole interaction partner for the PRE in neuronal cells nor under phorbol ester induction.
ASCs, ATMs and adipose immune infiltrating cells may interact with neighboring Muse-AT cells, affecting their lineage plasticity, adipose tissue differentiation and repair, and the production and recruitment of signaling molecules in times of cellular stress [26].
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