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These findings suggest that in cardiac myocytes PKA activity may inhibit subsequent PKD activation by multiple GqPCR pathways, including those stimulated by α1-ARs and ET1 receptors.
It has been proposed that attempts to reduce Müller cell gliosis may inhibit subsequent retinal degeneration and support neuroregeneration after reattachment [ 14, 35].
Although these pre-treatment methods reduced biomass recalcitrance and increased surface area (Ibbett et al., 2011), they are energy intensive and release compounds that may inhibit subsequent fermentation.
Given the status that meta-analysis may receive in decision-making, falsely large treatment effects and spuriously small P-values may inhibit subsequent trials on the specific questions.
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Dilution in water after adding bleach may reduce bleach-mediated damage to M. tuberculosis that can inhibit subsequent acid-fast staining [ 6].
Nevertheless, sustained proliferation of protoplasts (derived through this protocol) into calli compared to previous unsuccessful attempts may be a result of the reduction of polyphenols in the source tissue, which are known to inhibit subsequent protoplast division [ 39].
However, applied auxins usually inhibit subsequent bud development of cuttings in apple [3] and rose [4, 5].
It may be worthwhile to develop specific hyaluronan export inhibitors, because they could not only prevent proteoglycan loss and collagen degradation, but also inhibit subsequent reactions that lead to apoptosis of chondrocytes.
Since bacterial colonization of the implant is a prelude to clinical infection, antimicrobial modification of the devices may inhibit device colonization and subsequent infection.
Immediately after germination, ABA may inhibit the establishment and subsequent development of young seedlings, with this post-germinative arrest representing an early developmental checkpoint to slow seedling growth until better conditions arise [1] [3].
Given the known involvement of streptolysin in S. iniae virulence [ 28, 30], our results support the hypothesis that the immunoprotectivity of pSagE is probably due at least in part to its ability to induce production of specific serum antibodies, which, upon encountering S. iniae during subsequent infection, may inhibit the function of SagE and thus block S. iniae infection.
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