Sentence examples for may inhibit proliferation from inspiring English sources
There are three potential anticancer mechanisms for COX-2 inhibition, it may inhibit proliferation in epithelial cells, increase apoptosis, reduce angiogenesis.
Even the highest concentration, 50 μg/mL, may inhibit proliferation initially, but this effect only lasts for 1 day, as the cells appeared to recover.
Our findings suggest RB-K may inhibit proliferation through the assembly of transcription repression complexes, whereas RB-N is likely to directly inhibit the trans-activation function of E2F.
Thus, we speculate that oxymatrine may inhibit proliferation of Hep-2 cells through downregulation of HPV16E7 gene.
PKA is involved in regulation of cell proliferation by acting on transcription factors, for example it may inhibit proliferation by uncoupling Ras from c-Raf activation [ 2].
In contrast, it is difficult to time the maximal activity of cells expanded with vaccines, and chemotherapy administered after vaccination may inhibit proliferation of the desired cell population.
TGF- β cytokines may also inhibit proliferation and induce pro-apoptotic genes, such as the Bcl-2 superfamily members BMF and BIM, as demonstrated in primary cultures of human fetal hepatocytes, but they also upregulate anti-apoptotic genes, such as BCL -XL and XIAP.
From our standpoint, ghrelin may act as either antiapoptotic or proapoptotic factor and may enhance or inhibit proliferation in different cells, suggesting that these effects are cell type dependent and are presumably affected by specific cell microenvironment.
This result is in agreement with the notion that WFDC1 expression does not only correlate with low proliferation rate but may also directly inhibit proliferation when introduced exogenously.
In general TGF-alpha promotes cell proliferation while TGF-beta may stimulate or inhibit proliferation depending on the cell type and growth factor environment.
The specific downregulatory effect of PC on the expression of genes classified in cell proliferation suggests that PC may inhibit the proliferation of OA meniscal cells.
