Exact(1)
A possible mechanism is that cytoplasmic aggregated tau may inhibit processes such as the ERAD-proteosome pathway used by cells to degrade misfolded ER proteins, and thus preventing the normal degradation of these proteins, stimulating ER stress [ 39].
Similar(59)
Expression of Fn1 in white matter may inhibit oligodendrocyte process outgrowth and myelin sheath formation (Siskova et al., 2009).
Another point where vitamin D may inhibit inflammatory processes is through suppression of cytokine signaling and production.
For example, JH synthesis correlates with the number of vitellogenic ovarioles in nymphoids but not in ergatoids of Reticulitermes flavipes[ 6, 7], and an elevated JH titer may inhibit reproductive processes in immature alates of Zootermopsis angusticollis[ 5].
In addition to this, homocysteine and its metabolites may have a direct excitotoxic effect on the N-methyl-D-aspartate (NMDA) glutamate receptors in the brain and may inhibit methylation processes in the central nervous system [ 18]; therefore, its conversion is critical [ 19].
Consequently, KAT6B may facilitate but also inhibit processes leading to AAA formation.
Iron is needed for mitochondrial biogenesis during osteoclastic differentiation and reducing extracellular iron levels may inhibit this process and possibly overpower any HIF induced osteoclast formation.
Magnetite formation after reaction of Fe(II) with lepidocrocite has been observed previously [37], although high sulfate concentrations (not present in our study) may inhibit this process [2, 38].
On the other hand, high gene flow may inhibit the process of local adaptation.
LNG may inhibit the process of ovulation, fertilization or implantation [ 15- 20].
Despite the potential for cancer registries to provide researchers with access to large and representative samples, current registry protocols such as active clinician consent may inhibit this process.
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