Sentence examples for may inhibit platelet from inspiring English sources
These data suggest that nobiletin may inhibit platelet function through the elevation of cGMP and not through cAMP.
The current study attempted to clarify the role of CTRP9, a novel adiponectin paralog, in enhanced platelet activity and determined whether CTRP9 may inhibit platelet activity.
To gain more direct evidence that CTRP9 may inhibit platelet function, the effect of in vitro CTRP9 pre-treatment upon ADP-induced platelet aggregation was determined.
These prospective data also suggest that statins may inhibit platelets directly via yet unknown mechanism(s) possibly related to the regulation of the PAR-1 thrombin receptors.
Phenolic compounds may reduce the formation of free radicals, may inhibit oxidation of low-density lipoproteins (LDL) by chelating divalent metal ions and may also inhibit platelet aggregation and adhesion [ 38– 42].
The increased levels of VASP phosphorylation may directly inhibit platelet function mediated through the phosphorylation of myosin light chain kinase resulting in impaired calmodulin binding and therefore reduce cytoskeletal reorganization essential for platelet shape change (Onselaer et al., 2014).
Postulated mechanisms include the inhibition of prostaglandins which stimulate angiogenesis, inhibit apoptosis, and stimulate aromatase activity and thus increase estrogen levels; ASA may also inhibit platelet-induced adhesion of circulating tumor cells that initiate metastases [ 4].
Venom C-type lectins may activate platelets or inhibit platelet activation, but either mechanism serves the function of inducing thrombocytopenia.
Because platelets play an important role in the pathogenesis of cancer and cardiovascular disease, our findings that RXR ligands inhibit platelet activation may help to explain the efficacy of these ligands.
Furthermore statins may reduce the excitotoxicity of glutamate, inhibit platelet aggregation, and prevent apoptosis [ 143].
Tissue perfusion may furthermore be improved by the ability of iNO to inhibit platelet aggregation [ 47].
