Sentence examples for may inhibit pathways from inspiring English sources

The P38 kinase inhibitor SB202190 protected 1 mM SNP-mediated chondrocyte death only at 10 μM, which may inhibit pathways other than p38 (Fig. 5b).

HES1 is a downstream target and mediator of the Notch signaling pathway [ 45], suggesting that genistein treatment may inhibit Notch pathway activity.

We hypothesized that if treatment with a drug could reverse, at least in part, the gene expression signature of GBM and GSCs, this drug may have the potential to inhibit pathways essential in the formation of GBM and thereby treat GBM.

However, accumulation of Ptch1 within cilia in the absence of BBS components may inhibit Shh pathway activation.

Therefore, our results revealed that lipid peroxidation may inhibit mTORC1 pathway in synoviocytes, which may confer to the development of inflammations.

Taken together, all these data indicates that cadmium toxicity may inhibit AKT/mTOR pathway, which may contribute to the decreased glucose oxidations and energy productions in cardiomyocytes.

We propose that adiponectin may inhibit the apoptosis pathways mediated by p21/p53 and c-Myc at high glucose concentrations.

Taken together, these findings support the hypothesis that SRT501 and SRT1720 inhibit inflammation and are consistent with prior reports suggesting that SIRT1 may inhibit inflammatory signaling pathways [ 47- 52].

TNFAIP3 also interacts with TXBP151, an antiapoptotic protein, and may inhibit inflammatory signaling pathways such as TNF-induced NF- κB activation [ 33, 34].

Targeting two or more growth signaling molecules may serve to inhibit multiple parallel pathways which are collectively important for cell growth or may inhibit a single pathway more efficiently by suppressing more than one mediator along the pathway.

These data indicated that Ginkgetin may inhibit Wnt signaling pathway downstream of β-catenin destruction.