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This inherent self-assembly capacity may inhibit formation of regular, ordered and long structures and result rather into either amorphous structures, large and undefined sheets or branching tubular structures.
For example, blockade of B-cell trafficking may inhibit formation of autoantibodies [ 77].
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Ammonium sulfate is often used as a corrosion-preventing additive and may also inhibit formation of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs).
Potentially, agents that inhibit VEGF and other agents involved in neovessel formation may inhibit their formation and propagation.
According to the abovementioned antiglycation mechanisms, RGSE may inhibit AGE formation by decreasing the ROS formation or by scavenging the ROS formed in vitro by auto-oxidation of sugars and/or oxidative degradation of Amadori products.
OPA1 down-regulation may inhibit pore formation through a similar stabilization of the inner mitochondrial membrane, or the disturbances in cristae formation may alter the way Ca2+ is handled within the mitochondria (Piquereau et al., 2012).
Therefore, we hypothesized that pseudomonads and cyanide may inhibit biofilm formation through limiting the induction of one (or both) of two key loci required for biofilm formation, the epsA-O and yqxM-sipW-tasA operons [40] [45].
In addition, we have shown that TWEAK, alone and together with TNF-α, induces the expression by osteoblasts and osteocytes, in vitro and in ex vivo bone, of the bone formation inhibitor, sclerostin, via a MAPK-dependent pathway [ 16] suggesting a means by which TWEAK may inhibit bone formation during inflammatory bone remodeling.
Decreased respiratory complex activities caused by severe Cu deficiency may inhibit MPTP formation by increasing matrix ADP concentration or promoting oxidative modifications that reduce the sensitivity of the calcium trigger for MPTP formation.
It appears that (a) the amyloidogenic properties of silkmoth chorion peptides are encoded into the tandemly repeating hexapeptides comprising the central domain of silkmoth chorion proteins, and, that (b) suitable mutations, properly and carefully designed, greatly affect the strong amyloidogenic properties inherent in certain aminoacid sequences and may inhibit amyloid formation.
Thus, PTH infusion may inhibit bone formation, as judged by circulating biochemical markers, whereas daily injections confirm the potent anabolic actions of the hormone.
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