Sentence examples for may inhibit binding from inspiring English sources

Mutations in the open reading frame of the cyp51A gene can result in structural alterations to the enzyme, which in turn may inhibit binding of drugs.

In addition, tight junctions between cells growing at post-confluence may inhibit binding of serum factors to the cell surface, leading to the upregulation of CD26.

Together, these data raised the possibilities that iAs may inhibit GR binding or stability at the glucocorticoid response element (GRE), or alternatively, the binding of another promoter-associated protein essential for initiation and activation.

Apo A-IV, as with other Apo A proteins, has the capacity to bind fibrin and proteins of endothelial cells and monocytes, and therefore may inhibit plasminogen binding and plasmin generation [ 35].

However, capsule may inhibit C4bp binding to PorA [ 33].

In some cases, as illustrated in Figure 8, an excessive ligand density may inhibit the binding of NCs to target cells.

We have recently shown that close proximity of the scFv attached with the APF anchoring domain may inhibit the binding activity of a cell wall anchored scFv [ 25].

The results of this extensive mutational analysis are summarized in Figure 2B, and they suggest that seven residues (1,089 1092 and 1,097 1,099) of TIMELESS are implicated in its interaction with PARP1 and that phosphorylation of Thr1078 may inhibit this binding.

It is also possible that it is a result of methylation at the G C sequences either at guanine O or cytosine C, which may inhibit Sp1 binding and downregulate the hTERT gene.

As anionic heparin binds tightly to histone tails, and potentially changes the net charge of the nucleosome, heparin may in fact also inhibit binding of nucleosome-containing immune complexes to components of the GBM, like laminins and collagens.

Especially, the previous study has showed that Nap1 binding may inhibit non-nucleosomal binding of H2A H2B to genomic DNA [ 26].