The important role of TSH in growth as well as in function helps to explain how disruptions in the thyroid-pituitary axis may influence thyroid neoplasia in rodents.
Also, it has been reported that the thyroid hormone plays crucial roles in the cells proliferation and differentiation in human body, and various physiological and pathological stimuli may influence thyroid hormone synthesis [ 34, 35].
Furthermore, there are several factors not accounted for in this study that may influence thyroid function and lipid profile, including smoking and insulin resistance [ 14], as well as obesity and abnormalities in glucose tolerance.
The main strength of our study is the use of a biomarker of lithium exposure in urine combined with analysis of biomarkers for selenium, iodine, and cesium all elements that may influence thyroid function as well as sensitive markers in plasma of effect on the thyroid.
The discrepancy between our findings after exposure to isoflavones present in clover and experiments using soy protein isolates indicates that traditional soy based diets are safe (in this respect), whereas red clover extracts may influence thyroid hormone release and steroid synthesis at low doses.
Biological variables such as nutrition and lifestyle may also influence thyroid function.
This difference implies that other factors influence thyroid economy.
Additional research is needed for a better understanding of how phthalates may influence the endocrine system and thyroid function.
Exposure to ionizing radiation, particularly in childhood, may influence the incidence of thyroid carcinoma later in life [ 12].
We will highlight endocrine parameters that may influence these processes, including thyroid hormones, growth hormone (GH), cortisol, sympathovagal balance, and the immune system.
