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Taken together, these data suggest that the PF may influence neuronal activity in the direct and indirect circuits and could be considered as an additional component of the basal ganglia motor loops.
Our study extends the previous evidence found on pediatric population to the adult population, demonstrating that the higher synaptic dopamine levels associated with the presence of the Met158 allele may influence neuronal architecture in brain structures important for executive and emotional processing.
It has been reported to play a role in neuronal apoptosis during spinal cord development [26], and may influence neuronal growth in the hippocampus [27].
Inflammation is part of many neurological disorders and immune reactions may influence neuronal progenitor cells (NPCs) contributing to the disease process.
In the retina, Anxa5 has been localized to the ganglion cell layer [52], where it may influence neuronal function through binding of the postsynaptic scaffolding plasma membrane protein PSD95 [53].
Dietary composition may influence neuronal function as well as processes underlying synaptic plasticity.
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In addition, we propose here that tPA may differentially influence neuronal fate and signaling pathways as a function of its conformation with sc-tPA and tc-tPA.
With regard to NTC, activation of CB receptors may influence trigeminovascular neuronal firing by reducing expression of Fos protein, as suggested by our previous study [16].
Following stimulation with IL-1β, SGCs have been shown to be activated, which in turn may influence the neuronal responses [36].
Corticosteroids may influence sympathetic neuronal excitability, and activity in the sympatho-adrenal system may influence cortisol secretion [ 52, 53].
The targets, methods as well as the speed of rewarming may influence the neuronal recovery/damage following HIE.
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