Also, random integration may influence the molecular signatures of iPSCs by interrupting regulatory regions in the human genome.
The in vitro culture conditions may influence the molecular response to injury, potentially introducing artifacts.
In addition, stochastic genetic, environmental and microenvironmental factors may influence the molecular features of metastatic cancers.
These data suggest that tumor cells generated by the MMTV- PyMT and virus-based models have differences in their lineage plasticity, particularly at more advanced stages of progression, which may influence the molecular classification of tumors.
Generation time may influence rates of molecular evolution because organisms that copy their germline DNA more often per unit time are expected to incur more DNA replication errors, which could increase the mutation rate.
The authors describe how this device may influence future changes in molecular diagnostics in skin tumours.
Such variation may influence the performance of molecular diagnostic tests designed to detect mutations associated with drug resistance in M. tuberculosis isolates.
This molecular heterogeneity may influence the way tumor cells migrate, proliferate, and survive during tumor progression.
The rapid progress of high-throughput genomic sequencing and corresponding analysis tools in molecular diagnosis are revolutionizing the practice and it is a fact that for some monogenic epilepsies the molecular confirmation may influence the choice of the treatment.
The permeation of isolated parabens was also evaluated and the permeation characteristics, obtained by the Moser model, confirmed that lipophilicity and molecular weight may influence the systemic absorption of these compounds.
