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There are several potential mechanisms through which PM may influence lung health.
Many factors may influence lung cancer survival, including gender [ 2, 3], diagnostic age [ 4, 5], histological type [ 6, 7], and treatment modality [ 8- 10].
Our results are therefore consistent with other studies (Jaspers et al. 1997; Sexton et al. 2004) showing that air pollution exposures, such as those in urban environments, may influence lung cell function by altering the levels of gene transcripts and proteins associated with inflammatory response pathways.
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This suggests that IEAA does not mediate the association between smoking and lung cancer, but rather that IEAA may only influence lung cancer if a person is a smoker.
The relation between PM2.5 concentrations and lung cancer mortality rates varies spatially, and, in addition to PM2.5, there are other aetiologic agents that may influence the lung cancer mortality rate in different areas of China.
These findings together make SSRIs that enhance 5-HT action in the synaptic cleft, and may influence fetal lung function.
Parental smoking has been consistently related to childhood asthma [U.S. Department of Health and Human Services (DHHS) 2006] and TNF may influence the lung inflammatory response to tobacco smoke (Churg et al. 2003; Park et al. 2003).
Thus, adiposity may influence the lungs in several ways, e.g. through inflammation leading to asthma-like, obstructive changes, or in terms of a mechanical impact on lung function (restrictive changes).
Medication use on polluted days may influence symptoms and lung function.
While there is evidence that variation in the folate metabolism genes may influence prognosis from lung cancer, current data are insufficiently robust to distinguish individual patient outcome.
Recently, the overexpression of p130CAS has been observed in 61.9% of lung cancers suggesting that p130CAS may impact a variety of clinicopathological features of lung cancer and may influence the prognosis of lung cancer patients [ 23].
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