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In addition, diabetes and interpregnancy interval were included as they may influence healing after first OASI.
Randomization was controlled centrally from the university research office and stratified by centre, ulcer size (≤ 5 or > 5 cm), ulcer duration (≤ 6 or > 6 months), and whether they had a previous ulcer, as these factors may influence healing rates [ 51, 52] The 4LB system (control arm) was originally developed in the UK (Charing Cross Hospital) [ 53].
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Therefore, the tightness of the repair may influence wound healing.
Postoperative analgesics and antibiotics were not administered because these drugs may influence the healing process and thereby confound the interpretation of experimental data.
Furthermore, as sHA has pro-inflammatory and immuno-stimulatory properties (Termeer et al, 2000, 2002; Taylor et al, 2004; David-Raoudi et al, 2008), sHA may influence wound healing and inflammatory processes, in addition to contributing to the inflammatory status of tumours.
Purposive sampling (maximum variation) was employed to select facilities in which to conduct ethnographic observation and in-depth interviews, with variation in the following characteristics that may influence PU healing rates: facility ownership (i.e. for profit vs. non-profit), staff turnover, PU prevalence rates, and length of exposure to the intervention.
For example, Törkvist and colleagues tried to block CD18-dependent neutrophil infiltration to improve wound healing and concluded that neutrophils may influence the wound healing process differently in specific organs, based on diverse results in skin and intestinal tract [ 32].
Both may influence the autogenous healing potential of the slag-based ECC.
Furthermore, a prednisolone containing sealer that may influence the periapical healing [ 2] was used.
The strain, age and sex of the animals may influence the process of fracture healing.
Certain cytokines that are produced in liver may act as growth factors to facilitate wound healing and, hence, may influence liver regeneration.
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