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Impairment of renal medullary NO systems may induce sustained elevation of blood pressure and retention of sodium in fructose-fed rats.
Gold compounds may induce sustained remission of synovitis in subgroups of patients with rheumatoid arthritis, but the mechanisms are poorly understood.
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It is thus likely that the ability of R50E to disrupt DNA synthesis and cell proliferation induced by WT FGF1 may be a consequence of its defect in integrin binding and inability thereby to induce sustained ERK1/2 activation.
Enhanced expression of adhesion molecules in ApoE -/- SIRT1 +/- plaques Accumulating evidence suggests that chronic production of ROS may favor atherogenesis by inducing sustained endothelial inflammatory activation [ 2, 5].
Our model predicts that cyclic equibiaxial stretch at 1Hz generates a large increase in the amplitude of fiber stretch (cf. Fig. 2), which may induce the sustained cell retraction.
37 De Gannes et al suggest that TNFα inhibition may induce locally sustained INFα production 20 which in certain patients might lead to an outbreak of psoriasis and demonstrated lesional type 1 IFNα activity was increased in patients who developed psoriasis while on anti-TNFα therapy compared to psoriasis vulgaris.
Thus, production of inflammatory cytokines as a consequence of expression of ATX and LPA receptors in the transgenic mice may contribute to tumourigenesis by inducing sustained inflammation of mammary glands.
Our data imply that increases in plasma NPs may add another novel dimension to explain how liraglutide induces sustained weight loss.
Salmonella induced sustained TSLP release that did not reach the level of L. paracasei (Fig. 4).
The results presented here suggested a novel mechanism underlining MIF induced sustained ERK activation.
Insulin induces sustained and even stronger pathway activation than HRG.
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