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53 The concept that environmental cues may induce stable adaptive traits that can be passed between generations and influence phenotype has its theoretical roots in so-called "Lamarckian" inheritance.
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DNA methylation patterns which are largely established in-utero, induce stable changes in gene expression that may be sustained throughout the life span of an individual [33].
(77) Epigenetic repression of several genes (MLH1, p16, APC, and MGMT) in human chromate-associated cancers may reflect the presence of mutations in proteins regulating epigenetic stability or a direct ability of Cr VI) to induce stable transcriptional silencing.
This pathway can induce stable, multigenerational inheritance.
Continuous low-dose OT infusions induce stable uterine contractions.
Thus, redox modulation of cellular proteins comes in "different flavors"; while moderate reversible oxidations may increase protein activity, and a more sustained ROS may induce pathological modifications through stable interactions with lipids, proteins, and DNA (40).
Such kinds of noise may induce switching between the two stable states.
We conclude that BSH, in the provided doses, is safe in stable SCD patients and may induce changes in gene expression levels.
Still, growing bureaucratization is mentioned as a potential danger to this stable situation as this may induce growing dependence on the clinic's management, therefore resulting in interest dissatisfaction.
(The tilt of the tie-lines grows with the coupling parameter Λ.) Hence, if without coupling one monolayer is unstable and the other monolayer is stable, the coupling between them may induce phase-separation in both monolayers.
Loss of GPTMS surface stability with time (Supporting Information, Figures S6 and S7) may induce different changes in neoCM contractility relative to APTESglut surfaces with more stable laminin adhesion.
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