Sentence examples for may induce mutations from inspiring English sources
Arsenite therefore may induce mutations by two distinct mechanisms.
An excess of ROS may induce mutations, cancer, or cell death [ 47].
However, genotoxic treatments may induce mutations and translocations that result in secondary malignancies or recurrent disease.
Transposition events can shift, replicate, or delete copies of ISs within a genome, which may induce mutations that change fitness of the host cell [ 3, 6, 7].
This is thought to be largely due to exposure to aromatic amines, which, when activated, can react with DNA to form DNA adducts that may induce mutations in key cancer-related genes [ 1].
The acridine orange eliminates plasmids from prokaryotic cells [ 28], and although the conventional methods for curing plasmids by curing agents may induce mutations in the host chromosomal DNA [ 29], its use in plasmid detection is still being reported in clinical strains [ 30] and animal/environmental isolates [ 11, 31, 32].
Impairment of mitochondrial respiratory function not only reduces the supply of energy (which may prevent energy-dependent apoptosis) but also enhances ROS production, which may induce mutation and oxidative damage to mtDNA.
Long-term exposure to this drug may therefore induce mutations in critical genes especially those involved in the DNA repair pathways.
In attempts to find a prescreen for mutagens that may induce heritable mutations in mammals, an in vivo somatic mutation test has been developed in the mouse that uses a localized gene product (hair pigment), is relatively fast and cheap, and gives results that have some predictive value for point mutation induction in spermatogonia.
Thus, hypoxia may induce point mutations and DNA strand breakage leading to deletions, amplifications and genomic instability.
The transcription activator-like effector (TALE) nucleases, or TALENs, are customizable restriction enzymes that may be used to induce mutations at nearly any investigator-specified DNA sequence in zebrafish.
