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The process of reperfusion itself also contributes, rapidly changing the intracellular physiological environment including activation of pathways that may induce lethal myocardial injury.
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To the extent that those results reflect an underlying misunderstanding of the fitness consequences of mutation, this failure suggests that attempts to induce lethal mutagenesis may be misguided and have the unintended consequence of providing raw material for adaptation.
Mn exposure can induce lethal osmoregulation defects and a developmental delay in wild type worms.
Petroleum products kill larvae not by suffocation but by contact toxicity and used at non-lethal doses may induce resistance.
At sub-lethal concentrations, ClO2 may induce different behaviors in bacteria, with a study indicating B. subtilis formed biofilms at sub-lethal exposures to chlorine dioxide (Shemesh et al. 2010).
Thus, at non-lethal doses, it may induce a preconditioning response in neurons, and protect against subsequent injury.
Such compounds may elevate specific ROS that are less effective at inducing cell death or may induce oxidative stress in subcellular compartments that are less susceptible to lethal damage.
A high prevalence of Tregs within tumors is associated with more lethal PCa, suggesting that therapeutic blockade of these cells may induce beneficial clinical response.
A high prevalence of regulatory T cells within tumours is associated with more lethal PCa [ 29], suggesting that therapeutic blockade of these cells may induce beneficial clinical responses, by facilitating the generation of effective cytotoxic immune responses.
It may induce nothing more than vertigo.
Warning: may induce paranoia around computers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com