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A possible explanation is that the adjuvant alone may induce innate immune responses that can provide a certain level of protection against viral infections.
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In mice, DNA damage-induced IL-6 secretion by thymic epithelial cells establishes a chemo-protective niche for lymphoma cells, while p53-induced cytokine release may induce both innate and adaptive immune responses leading to tumor cell clearance., It is thought that DNA damage accumulation with aging causes chronic inflammation that contributes to tissue dysfunction and immune aging.
Editing of endogenous RNA duplexes may lower the risk that they aberrantly induce innate immune responses.
If correct, this implies that some cyanobacterial products possess ligands that induce innate immune responses, and such responses may need to be considered in terms of their potential to direct pathological changes in the liver and other organ systems.
Similarly, studies in mammals reveal that damaged mitochondria also release DNA fragments and formyl-peptides that can induce innate immune response genes [ 40], and therefore this may be an additional mechanism for innate immune response gene induction during aging that is a consequence of a failure in mitochondrial maintenance.
Gliadin peptides can induce innate and adaptive T cell-mediated immune responses.
Emergency vaccination might induce innate immunity.
These results suggested that Adv should induce innate immune responses in the iLNs.
On the other hand, reovirus is expected to induce innate immune responses even in tumor cells.
This opens an intriguing possibility for immune therapy; to use one single peptide that may trigger antigen-specific T cells and may enhance this response by inducing innate immunity through TLR triggering at the same time.
It may induce nothing more than vertigo.
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