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Thus, as well as the mechanisms postulated in adults, these data suggest that infection may induce focal intracranial arteriopathy, probably inflammatory, in some children with AIS.
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PPARγ ligands induce focal adhesion disassembly and decrease in FAK phosphorylation, which may be involved in induction of apoptosis [ 25, 27].
In the present study tMCAO was used to induce focal brain ischemia.
The transient middle cerebral artery occlusion (tMCAO) model was applied to induce focal cerebral ischemia as described elsewhere [45], [46].
Interestingly, AD pathology is known to induce focal demyelination and degeneration of oligodendrocytes [ 180].
Repeated high force loads are known to induce focal microtrauma in cartilage [ 120, 121].
These results suggest that treatment with PMC-12 may induce beneficial effects for improvement of memory function in a focal cerebral ischemia model.
One possibility is that longterm NeoA treatment, by virtue of its ability to dismantle focal adhesions and release cells from the substratum, may induce the anoikic state of apoptosis that often occurs when adherent cells are maintained in suspension [35].
Several treatments used in oncology may induce changes in normal bone marrow and in pathologic marrow affected by diffuse or focal pathology.
It may induce nothing more than vertigo.
may induce stress [2].
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