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Oxidative stress is a process that can cause damage to membranes, proteins and also to DNA, which may induce apoptosis [6].
These findings suggest that BIRD-2-induced Ca2+ elevation may induce apoptosis by a different mechanism in SCLC cells than in lymphoid cells.
This suggests that CUR may induce apoptosis and enhance BUS-induced apoptosis by downregulating the expression of survivin in KG1a cells.
The more potent apoptosis-inducing activity of 6-4PP lesions may induce apoptosis and "erase" the damaged cell, thus decreasing its carcinogenic potential.
The results demonstrated that these compounds may induce apoptosis through a mitochondrion-dependent pathway.
By contrast, blockade of p27 may switch the IDO-Kyn-AhR cascade to the JAK-STAT1 pathway, a signalling that may induce apoptosis via caspases 2, 3 and 7 (refs 42, 43).
Western blot and qRT-PCR (quantitative real-time PCR) experiments demonstrated that compound 6r may induce apoptosis through both of intrinsic and extrinsic apoptosis pathway.
GCs may induce apoptosis by directly regulating typical apoptosis or survival genes or by inducing cellular distress that triggers the apoptotic cascade [38].
AgNPs may induce apoptosis via oxidative stress (Arora et al. 2008; Gopinath et al. 2008), since many studies have implicated intracellular ROS in the signal transduction pathways leading to apoptosis (Ott et al. 2007; Ueda et al. 2002).
Similar(2)
Growing evidence suggest that, in the presence of toxic stimulus, the mitochondrial Ca2+ uptake may induce apoptosis in a variety of pathological conditions38.
Poricotriol A from Poria cocos may induce apoptosis in leukemia HL-60 cells and lung cancer A549 cells [ 32].
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