Sentence examples for may induce aberrant from inspiring English sources

DNA methylation, together with histone modifications may induce aberrant gene expression in many tumors [156].

Taken together, the MDS and Venn diagrams show that toxicants may induce aberrant DNA methylation events that are common in cancer.

According to Sigel et al. [ 31], the replacement of Zn2+ with Cd2+ in many enzymes and transcription factors may induce aberrant gene expression, resulting in the stimulation of cell proliferation.

Over-expression of EGFR has been observed in a variety of tumour types and it is thought that this may induce aberrant signalling, giving rise to uncontrolled cellular growth [reviewed in [ 61]].

Normal methionine levels may not induce aberrant DNA methylation [ 43].

Smoking may also induce aberrant promoter DNA methylation, thus silencing regulatory genes (e.g., ECAD, p16, MGMT, and DAPK) in tumor progression (Russo et al, 2005).

Another report showed that IL-4 induced an aberrant activation of Stat3 in GBM cells but not in normal human astrocytes, and speculated that IL-4 induce aberrant activation of Stat3 may contribute to the pathogenesis of GBM cells [ 8].

Mutations that disrupt G-CSFR ubiquitination at lysine 762 induce aberrant receptor signaling and hyperproliferative responses to G-CSF, which may contribute to leukemic transformation.

Asbestos fibers induce aberrant cell signaling, leading to proto-oncogene activation and chemoresistance.

Thus, nucleotide substitutions in these sequences can induce aberrant splicing.

Maternal diabetes has been shown to induce aberrant CNCC development in diabetic offspring [ 17].