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For example, antisense PNAs act directly through steric hindrance of translation initiation and may indirectly trigger decay of repressed transcripts, whereas antisense RNAs may act both by steric hindrance and by direct activation of dsRNA-mediated cleavage at the target site.
Instead, the induction of NADPH-consuming amino-acid pathways in conditions of NADPH limitation may indirectly trigger the transcription of a set of PP pathway genes.
This decision was based on observations that changes in the activity of Hxk2 lead to an array of effects, namely altered metabolism, which may indirectly trigger other regulatory responses [ 38, 44].
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When health authorities set national targets for consumption of locally produced medicines, they may actually indirectly trigger irrational prescription and/or decreased financial access.
These toxic (by-) products, may directly or indirectly trigger pathways mentioned above and hence contribute to tau phosphorylation.
12 Similar findings were reported by Sutton et al; the 5-year mortality rate was 36%. 13 Engel hypothesised that death may result from prolonged asystole often following severe vasodepressor syncope, or that prolonged asystole could indirectly trigger malignant tachyarrhythmias.
Absent clear congressional authorization, such action violates the Constitution because it would indirectly trigger either "taxation without representation" or confiscation without compensation.
Developers had to rely on service hooks to indirectly trigger Lambda functions.
Critics also charge that Expanded Choice could indirectly trigger more nursing-home admissions.
Anticancer therapies that target DNA integrity or replication indirectly trigger cell death in tumors.
Therefore, further studies are needed to determine whether activation of NHE1 can directly or indirectly trigger ERK1/2 phosphorylation.
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