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This study demonstrates that a dynamic susceptibility contrast-magnetic resonance imaging (DSC-MRI) perfusion parameter may indicate vascular abnormality in a brain tumor model and reflects an effect of dexamethasone treatment.
There are specific signs which may indicate vascular invasion with variable accuracy proximity of the mass to a vessel (73%), loss of the interface between the mass and vessel (78%) and irregularity of the venous wall (87%) [ 21].
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This may indicate that vascular ultrasound parameters are less robust in patients with mild congestion and may show the greatest change during initial management.
Increased levels of endothelial EVs and their procoagulant activity may indicate a vascular injury associated with a hypercoagulable state in AML.
In addition, decreased Hcy levels may indicate improved vascular health.
Carotid intimal medial thickness (IMT) was highest in CKD patients which may indicate advanced vascular lesions in that population.
In this concept, hyperglycaemia-induced perturbation of hyaluronan metabolism, characterised by increased hyaluronidase activity with subsequent increased plasma hyaluronan levels, may indicate increased vascular vulnerability.
These antibodies indicate vascular and thrombotic complications and oxidative modification of lipoproteins [ 52, 53] and may represent an increased risk of atherogenic and inflammatory complications.
Central retinal artery occlusion and ischemic optic neuropathy were also reported previously, which may indicate possible ocular vascular involvement as well as central vascular system in migraine [ 7– 9].
This reduction may indicate an inability of vascular permeability and glomerular circulation due to vascular defects which correlate to aneurysm and cystic formation in the mesangiolytic glomeruli.
Especially, type 3 fluid status (manifested as normal NT-pro BNP and abnormal BIVA) may indicate overhydration but without vascular volume expansion, a condition typically presented by patients with nephrotic syndrome and in some receiving peritoneal dialysis [ 11].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com