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Locking screw breakage has been considered a "self-dynamization" procedure, which may indicate progression of fracture healing [2].
The re-expression of TERT may indicate progression from bronchiolo-alveolar carcinoma to adenocarcinoma [ 7, 51].
Therefore, increases in plasma levels of SP-D and KL-6 in patients with ALI/ARDS may indicate progression to the proliferative phase.
The predominance of extrapulmonary (mostly pleural) disease among healthcare workers may indicate progression to disease from newly acquired primary infection rather than reactivation of latent TB.
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4 5 21 22 These are frequent symptoms in advanced patients with cancer, and may indicate disease progression.
Therefore, particular attention should be paid to progressive loss of R-wave sensing amplitude during follow-up, which may compromise adequate device function and may indicate disease progression.
Nevertheless, given that differential CAR expression may indicate a progression step during malignant transformation, these previous findings might reflect the possible complex function of CAR.
In that case, the snoRNA, cellular level of which rises/drops rapidly, may not play a key role in the pathology, but the alteration itself may indicate tumor progression and reflect metastatic potential [ 37].
Our findings suggest that a high serum hepcidin-25 level may indicate the progression of RCC, and that upregulation of hepcidin mRNA expression in tumor tissue may be related to increased metastatic potential.
Findings that demonstrate statistical non-significance for this association in a screen-detected population may indicate the likely progression to developing depression following a diagnosis of diabetes.
The induction of topo II α may indicate that the progression of DNA replication is halted by pemetrexed-induced DNA damage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com