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Because lack of physical activity may indicate frailty and severity of diseases, we also performed further sensitivity analyses adjusting for physical activity with a two year lag or excluding participants in the lowest fifth of physical activity.
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One could assume that patients with very low BMI (<18.5) would also have a worse survival prognosis, because very low BMI may indicate higher frailty and malnutrition at diagnosis.
A cut point of > = 0.25 was used to indicate frailty [ 4].
While the former finding may indicate that acquisition of pneumonia is a marker of frailty, the latter may indicate that this frailty can be partly offset by use of HAART.
The "pre-frail" categorization is congruent with the literature: pre-frailty is an intermediate status that may indicate an increased risk of adverse outcomes [ 17, 19, 60].
These analyses may indicate the existence of a strong genetic influence on individual frailty associated with mortality caused by heart diseases and CHD in both, males and females.
The diversity of social ties might exert a beneficial effect on frailty [ 34, 36], while living alone may indicate poorer social ties [ 21].
This may indicate difficulty concentrating.
It may indicate a trend.
It may indicate jealousy.
It may indicate tooth decay.
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CEO of Professional Science Editing for Scientists @ prosciediting.com