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These results may indicate cell type-specific effects of NOX2 in the development of cardiac hypertrophy and fibrosis.
Their release may indicate cell turnover and the information supplied by TPA may be distinctly different from the information supplied by the markers of tumor burden CA 15-3 and CEA [ 2, 3].
Moderate increases in sugars commonly found in cell walls such as cellobiose, xylonic acid and arabinose, which may indicate cell wall modifications, were measured in sugar beet Fe-deficient root tips.
There were both similarities and differences between the genes that were differentially expressed in our study and those highlighted by a recent gene expression study (Ghosh et al, 2011) of HER2 homodimers and HER2/HER1 or HER2/HER3 heterodimers in HER2-expressing MCF10A cells (Supplementary Figure 2C and D), which may indicate cell- or disease-specific signalling.
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Here, using BSP, we observed methylation variability in two CpG sites that may indicate cell-specific methylation.
AZA > Bz showed slightly higher Ki67+percentt of cells than AZA > DMSO, which may indicate cells arrested in G1 (which still stains Ki67) while the AZA treatment might have the majority of cells in a G0.
Increased MUC13 expression has been found to induce morphological changes, including scattering of cells through interference with the function of cell adhesion molecules [14]; thus, an increased expression along with differentiation may indicate enhanced cell-cell adhesion.
IL-17A staining was also seen on some CD3 negative cells, which may indicate NK cells and other types of cells that produce IL-17A.
Increased Cr levels may indicate glial cell proliferation or higher glial cell metabolism and tissue repair mechanisms [32].
This may indicate physiological cell life turnover or programmed cell death.
This may well indicate cells at G2 phase of the cell cycle.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com