Furthermore, studies of other pathogens causing UTI have reported responses involving iron acquisition systems and genes involved in sugar and amino acid metabolism [18], [19], which may indicate that bacteria suffer from glucose and iron limitation during growth in human urine.
The overwhelmingly high levels of EQU relative to other phytoestrogens may indicate that bacteria mediate formation of this compound not only in vivo, but also during lagoon storage.
These results may indicate that symbiotic bacteria in eggs are important to fly development and intensify fruit rot.
A burst of live S. aureus in the conditioned media may indicate that the bacteria either suddenly proliferated intracellularly, with large numbers of bacterial cells being released into the media after hMDM lysis, or that a small number of surviving intracellular bacteria escaped intracellular confinement and multiplied vigorously in the media, killing the hMDMs in the process.
Interestingly, all amino acids essential for function of both domains are conserved, which may indicate that these bacteria arrange a functional "all in one" PAR eraser.
Such mechanisms may indicate how the bacterium adapts to the host, a prerequisite for an enhanced accumulation of genomic mutations associated with resistance.
The presence of this system on RGP47 may indicate that the bacterium acquired and fixed it in its quest to thrive in the mycosphere at the expense of exuded glycerol.
On the other hand, detecting the same 16S rRNA variant in a female tick (294 9) and in a nymph (294 6; Figure 1) that fed side by side on a yearling, may indicate that the bacterium was acquired by co-feeding transmission (between infected and noninfected ticks).
This outcome is attributed to an adaptation of the microbiota of antibiotic administration and may indicate a substitution of bacteria sensitive to antibiotics by bacteria resistant to them.
However, small genome size, high GC content and lack of ~70 genes also missing in obligate intracellular bacteria may indicate that DSM 24701 has taken steps on the one-way road toward gene loss like that which led other bacteria to become host dependent.
