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The observed changes in D2 receptor sites may indicate altered DA neurotransmission following stress and alcohol exposure.
Nonsense or frameshift mutations were relatively rare, given that TP53 is a tumor suppressor gene, and the predominance of missense mutations may indicate altered function of TP53 rather than complete inactivation.
We speculate that this result may indicate altered gene expression in non-endothelial components of the blood-brain barrier.
Although the sequence divergence in the B. pumilus photolyase may indicate altered function, B. pumilus may rely on a combination of other factors for its UV resistance properties.
That one falls as the other rises may indicate altered specificities for different predatory-versus-free-living proteins and altered accessory proteins involved in binding to them to carry out the cis-trans isomerisation and conformational alterations.
The observed lower DHA levels despite higher precursor ALA levels may indicate altered biosynthesis in the PTPE placenta.
Similar(46)
Clearly, they provide the most clinically relevant indication of intervention effects, but it is important to realise that symptoms by themselves may not necessarily indicate altered immune function because other non-immune system-mediated mechanisms may be responsible for the changes in symptom scores.
Thus, disturbance in tooth eruption with altered number of teeth may indicate an altered physical development and vice versa; an altered physical development may be related to a disturbance in tooth eruption.
Further studies may indicate whether altered perfusion, nutrients, microbial flora, inflammation, or aerobic glycolysis contributes to these observations.
The increase in systolic blood pressure (121.2 to 131.1 mmHg, P = 0.00), however, may indicate an altered hemodynamic circulation rather than a major deterioration.
Our finding of an increase in cortical thickness that is negatively correlated with age may indicate an altered developmental trajectory than in non-depressed controls, which may exhibit characteristic pruning during development resulting in lower volumes, thinner cortices, and decreased function in the DLPFC.
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