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Upregulation of GSTs in AA astrocytes may indicate active detoxification activity by GSH metabolizing enzymes, resulting lower levels of GSH as we demonstrated in vitro and perhaps in vivo.
These transcripts may indicate active ongoing transposition activity in Æ. ægypti or, more likely, they may represent regulatory elements suppressing transposition of relatively recent genome invasions.
This domain also has high stream gradients with low sinuosity which may indicate active deformation.
Changes in gamma-gultamyl amino acids, associated with elevated cysteine-glutathione disulfide (change 0.24, nominal p value of 0.03), between high- and moderate-performance athletes may indicate active gamma-glutamyl cycle that plays an important role in the glutathione-mediated radical detoxification during oxidative stress [45].
This residual viremia may indicate active virus production, as the half life of free virus particles is short [8], [9].
The coordinate increase in CCL2 and TNFα responses observed in the pulmonary TB group, may indicate active monocyte recruitment to the lungs which are likely to facilitate granuloma formation and localization of M. tuberculosis infection.
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Hepatitis B core antigen status reflects exposure and may not indicate active infection.
Moreover, it has been suggested that a threshold level of hTERT protein is required in order for telomerase to become active, therefore low levels of hTERT mRNA may not indicate active telomerase [ 57].
Detectable quantities of the SNAI I (Snail) and TCF-3 (E2A) proteins in tumour and normal stromal cultures may also indicate active EMT/MET processes both in tumour stroma and surrounding presumably normal tissue.
Our data indicate that a significant proportion of CBCs occurring shortly after the initial cancer may represent or indicate active systemic disease.
This result may indicate that active Ca2+ absorption occurs in the hindgut, and this absorption may be activated if dietary Ca2+ content is reduced or demand increased.
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