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Interestingly, phospholipids are known to accelerate the rate of ATP ADP exchange [42] supporting the suggestion that the attachment of RbbA to the membranes may indeed enhance its ability to exchange bound ADP to the active bound ATP form which is needed for protein synthesis.
Two facts may indeed enhance the role of OR in the field of development and evaluation of anti-cancer drugs.
However, we suggest that such evolution does not necessarily undermine control, and may indeed enhance its efficacy.
This is counterintuitive, as smoking cessation does not, as commonly stated, negatively affect outcomes of treatment for other substance misuse, but may indeed enhance them [ 29].
Indomethacin increased IL-1β-induced IL-1Ra secretion in synovial fibroblasts and de-differentiated chondrocytes, suggesting that inhibition of COX-2 may indeed enhance IL-1β-induced IL-1Ra production.
Conducting school oral health screening programmes may indeed enhance early diagnosis of the lesion of a large number of cases as the results of the study by Oyedele et al. [ 19] showed.
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Most importantly, they provide evidence that combination therapy may indeed greatly enhance treatment success and that it should be followed up with experiments that study its use in an animal model.
Small proof-of-concept clinical trials in cancer patients indicate that the efficacy of anti-cancer vaccines may indeed be enhanced by chemotherapy (Kaufman et al, 2008; Nistico et al, 2008), however additional studies on scheduling and appropriate combinations are warranted.
The experience appeared to solidify and indeed enhance their altruism.
However, the possible occurrence of a selection bias does not invalidate the clinical relevance of our results and indeed may enhance it.
This result raises the possibility that AR may indeed reduce the ER stress response by enhancing Grp78/BiP translation or protein stability and in turn stabilizing the ER.
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