Sentence examples for may increase systemic from inspiring English sources

Strong P-gp inhibitors may increase systemic absorption and decrease elimination of P-gp substrates, resulting in increased exposure.

Our study adds to the conclusion that pollution may increase systemic inflammation even in young healthy subjects.

In vivo data suggest that the co-administration of ketoconazole at normal clinical doses with 4-HPR may increase systemic exposure to 4-HPR in humans.

Early microvascular changes and dysregulation may increase systemic BP, which in turn may lead to further retinal vascular changes in a self-perpetuating cycle.

OATP1B1 genetic variants with decreased activity may increase systemic exposure, and hence the chance of dose/concentration related adverse drug reactions.

The particle pollution in CAD patients during physical activity may increase systemic arterial vascular narrowing, as manifested by increased peripheral blood pressure and HR [ 44, 45], and promote arterial vasoconstriction via altering cardiovascular autonomic nervous system balance [ 46– 46].

EPI® treatment further significantly increases both VEGF and VEGF-R1 thus suggesting an active role in maintaining blood flow in the microcirculation and also may increase the systemic level of soluble anti-inflammatory and cytoprotective mediator events that can improve the recovery from injury [ 30].

The implementation of the clearing obligation required by this Regulation may increase the systemic importance of CCPs and the need for liquidity.

If blood pressure fell with a rise or no change in cardiac output, the primary problem is a decrease in systemic vascular resistance and, although increasing cardiac output may help to some extent, it may be necessary to pharmacologically increase systemic vascular resistance with a drug such as norepinephrine.

The present findings suggest that regularly skipping breakfast may elicit adaptations to progressively increase systemic glucose appearance and/or impair glucose disposal when the overnight fast remains unbroken until after 1200.

This may occur because the prosthetic material within an AVG may induce increased systemic inflammation.