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This study investigates whether this exercise may increase mechanical loading on the vocal folds.
Similarly, in vitro culture of cells on the biomimetic scaffold may increase mechanical properties through deposition of extracellular matrix proteins (Fisher et al. 2015) while also contributing to neotissue formation if localized to the lesion (Shimomura et al. 2015).
Although BMI may increase mechanical load on the plantar aponeurosis, overweight is associated with microvascular complications in diabetes, insulin resistance, hypertension, and an atherogenic profile.
Settings for the respiratory rate are debated, with some authors suggesting that rapid respiratory rates may increase mechanical lung stress [ 22].
The use of bone graft to increase mechanical strength remains controversial; whilst it may increase mechanical strength, some authors have suggested that opening wedges can be left unfilled [ 3], which avoids the risk associated with gap filling with inert substances [ 15].
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This process may increase the mechanical stress in the deep zones of the hyaline articular cartilage, contributing to the acceleration of OA (Goldring & Goldring 2010).
Results indicate that the encapsulation of small hydrophobic molecules (<400 Da) may increase the mechanical integrity of microfilaments whose crystallinity is also increased as a result of the process.
Surgeons in favor of bone grafting believe that it could stimulate fracture healing, leading to early full weight-bearing; may prevent posttraumatic arthritis; and could increase mechanical strength, thus helping to prevent significant late collapse [7, 8].
A pressure or volume overloaded heart may exert increased mechanical strain at a cellular level.
In other cases, obesity (Zanetti et al. 2003), overlying degenerative cartilage changes, meniscal tears (Ahlbäck et al. 1968), and meniscal injury (Robertson et al. 2009) may cause increased mechanical loading in the affected condyle, resulting in subchondral fracture.
In previous studies, it was hypothesised that the reduction of ROM caused by the cam morphology may increase loading and mechanical stress at the pubic symphysis level and on surrounding structures [69].
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