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Interestingly, in labour at full dilatation pre-eclamptic patients had significantly higher levels of activin A and sFlt-1 compared to pre-labour levels, suggesting the process of labour and/or induction of labour may increase maternal circulating levels of these proteins in pre-eclampsia.

Further, an emphasis on the positive aspects of pregnancy may increase maternal QoL.

Paternal factors may increase maternal physiological investment in the fetus without exacerbating obstetric risks by driving greater limb lengths and lean tissue.

Compared to previous studies, which have demonstrated that a higher physical accessibility may increase maternal services utilization in Tanzania [ 50], Ghana [ 54] and Nepal [ 55], our results have not shown strong evidence that mothers who lived near to a health facility attended more frequently PNC services as compared to those who lived far from a health facility.

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Respondents from countries that monitored weight indicated that the practice is aimed at reducing adverse perinatal outcomes, while those from countries who did not recommend routine weighing reported concerns that weighing may not impact outcomes and may also increase maternal anxiety.

The male-to-female sex ratio may increase with increasing maternal gravidity and parity, and to the best of our knowledge, this phenomenon has not been observed previously.

However, although the milk-to-blood lead ratio may increase as maternal blood lead concentrations exceed 40 μg/dL, the milk-to-plasma lead ratio should not change significantly at higher maternal blood lead concentrations.

Delivery of a macrosomic fetus may increase both maternal and perinatal morbidity.

However, we hypothesize that chronic subclinical infections may cause increased maternal cytokine levels sufficient to affect vascular endothelial function, and so prime individuals for the subsequent development of preeclampsia.

Length of time from pregnancy to interview and multiple jobs during the exposure period of interest may increase errors in maternal recall of paternal occupations.

Access to cesarean deliveries is associated with improved maternal and perinatal outcomes in countries with poor access to obstetric care, however, high cesarean rates may contribute to increased maternal morbidity and mortality [ 6].

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