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Swelling of hepatocytes, interstitial edema, and infiltrates of inflammatory cells may increase liver stiffness in patients with acute hepatitis [ 45].
Recent studies indicated that impaired hepatic lipid and lipoprotein settling and increased oxidative stress in liver cells may increase liver fat accumulation and result in insulin resistance [ 21, 22], thus increase the hepatic glucose production and export to the peripheral circulation, as a result, raise the level of serum glucose [ 23].
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Therefore, metformin intoxication may either increase liver lactate production or decrease clearance (along with gluconeogenesis) [ 13, 16].
PEG presents the advantages of being safe and multifactorial agent and may constitute a novel strategy to increase liver graft preservation.
These results suggest that reduced levels of haptoglobin may reflect increased liver damage.
Exposure to C5H5N may cause increased liver weight and hepatic lesions (U.S. EPA 2004).
PSE with selective TACE is tolerable in most cases, but the extent of PSE with TACE in a wide area of the liver may increase the risk for fatal liver failure.
Although PSE with TACE was safe and tolerable for most patients, the extent of PSE with TACE in a wide area of the liver may increase the risk for fatal liver failure.
Thus, any improvement in the preservation of liver grafts may increase the number of viable donor livers available for transplantation.
Several studies have suggested that the homing of circulating lymphocytes to the liver may increase during inflammation and enhance hepatic inflammation [26].
Sulfonylureas have been associated with hyperinsulinaemia, which may increase the risk of liver cancer (Bowker et al, 2006; Decensi et al, 2010).
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